Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726609 | 0.93 | SLC6A2 (0.40) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11750925 | 0.87 | CYP1A2 (0.48) | MAPK1MAPK14KCNH2SCN3APPARG | |
| SCHEMBL11727800 | 0.87 | L3MBTL1 (0.41) | MAPK1MAPK14KCNH2SCN3ASLC6A2 | |
| SCHEMBL11747843 | 0.86 | KDM4E (0.41) | MAPK1MAPK14KCNH2SCN3APOLB | |
| SCHEMBL11747404 | 0.81 | MEN1 (0.42) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11751982 | 0.81 | AGTR2 (0.37) | MAPK1MAPK14KCNH2SCN3APPARG | |
| SCHEMBL11749562 | 0.79 | MEN1 (0.41) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11755837 | 0.79 | KCNH2 (0.33) | KCNH2SCN3ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11755415 | 0.78 | MTNR1A (0.34) | MAPK1MAPK14KCNH2SCN3ABTK | |
| SCHEMBL11749123 | 0.77 | KCNH2 (0.36) | MAPK1MAPK14KCNH2SCN3ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051170-A | Diphenoxyacetic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |