Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | PTGFR | P43088 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725181 | 0.88 | TBXA2R (0.43) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11726209 | 0.88 | KDM4E (0.44) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11731623 | 0.88 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11731322 | 0.88 | ADRB2 (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11727274 | 0.87 | TBXA2R (0.38) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11734063 | 0.87 | TBXA2R (0.40) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11733959 | 0.86 | MAPK1 (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11728653 | 0.86 | TBXA2R (0.38) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11728772 | 0.83 | TBXA2R (0.37) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11727609 | 0.81 | LTA4H (0.38) | TBXA2RPTGER1PTGFRPTGER3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |