Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727274 | 0.89 | TBXA2R (0.38) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11732610 | 0.87 | GRM2 (0.34) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11729918 | 0.86 | LMNA (0.44) | LTA4HLMNATBXA2RPTGER1PTGFR | |
| SCHEMBL11726209 | 0.83 | KDM4E (0.44) | LMNATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11731322 | 0.83 | ADRB2 (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11731623 | 0.83 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11734063 | 0.83 | TBXA2R (0.40) | LMNATBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11725298 | 0.82 | CYP1A2 (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11733959 | 0.82 | MAPK1 (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11728653 | 0.82 | TBXA2R (0.38) | TBXA2RPTGER1PTGFRPTGER3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |