Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 3/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728916 | 1.00 | LTA4H (0.39) | LTA4HTBXA2RNFKB1NFKB2RELA | |
| SCHEMBL11729663 | 0.89 | PTGFR (0.38) | TBXA2RPTGFRPTGER3PTGER1 | |
| SCHEMBL11729672 | 0.89 | PTGFR (0.38) | TBXA2RPTGFRPTGER3PTGER1 | |
| SCHEMBL11733235 | 0.87 | GRM2 (0.33) | TBXA2RPTGFRPTGER3PTGER1 | |
| SCHEMBL11733249 | 0.87 | GRM2 (0.33) | TBXA2RPTGFRPTGER3PTGER1 | |
| SCHEMBL11728900 | 0.86 | PTGFR (0.42) | LTA4HTBXA2RPTGFRPTGER3PTGER1 | |
| SCHEMBL11728896 | 0.86 | PTGFR (0.42) | LTA4HTBXA2RPTGFRPTGER3PTGER1 | |
| SCHEMBL11729925 | 0.86 | LTA4H (0.43) | LTA4HTBXA2RPTGFRPTGER3PTGER1 | |
| SCHEMBL11734107 | 0.84 | TSHR (0.42) | TBXA2RPTGFRPTGER3PTGER1KDM4E | |
| SCHEMBL11736071 | 0.84 | ADRB2 (0.40) | TBXA2RPTGFRPTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |