Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680918 | 0.87 | CYP2C19 (0.74) | CYP2C19ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL10333162 | 0.85 | CYP2C19 (0.72) | CYP2C19ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL10334221 | 0.81 | CYP2C19 (0.66) | CYP2C19ALDH1A1LMNAKDM4EEPHX2 | |
| SCHEMBL11729073 | 0.81 | CYP2C19 (0.64) | CYP2C19ALDH1A1LMNAKDM4EEPHX2 | |
| SCHEMBL9845547 | 0.75 | CYP2C19 (0.60) | CYP2C19ALDH1A1LMNAKDM4EEPHX2 | |
| SCHEMBL7886122 | 0.68 | HPGD (0.57) | ALDH1A1LMNAKDM4EHTTF2R | |
| SCHEMBL18664790 | 0.66 | CETP (0.56) | ALDH1A1KDM4EF2RNPC1HPGD | |
| SCHEMBL6656873 | 0.64 | FEN1 (0.52) | ALDH1A1LMNAKDM4EHTTNPC1 | |
| SCHEMBL11729050 | 0.63 | ALDH1A1 (0.43) | CYP2C19ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL11728123 | 0.62 | CYP2C19 (0.44) | CYP2C19ALDH1A1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017299-A | Phthalimide derivatives as plant growth regulants | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3940419-A | Phthalimide derivatives and their use as plant growth regulants | AMERICAN CYANAMID COMPANY (US) | 1976-02-24 | — | — | US | disclosed |