Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333162 | 0.99 | CYP2C19 (0.72) | CYP2C19ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL11729065 | 0.87 | CYP2C19 (0.71) | CYP2C19ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL10334221 | 0.84 | CYP2C19 (0.66) | CYP2C19ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL11729073 | 0.83 | CYP2C19 (0.64) | CYP2C19ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL9845547 | 0.82 | CYP2C19 (0.60) | CYP2C19ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL11728123 | 0.75 | CYP2C19 (0.44) | CYP2C19ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL3020106 | 0.73 | ALDH1A1 (0.52) | CYP2C19ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL11810343 | 0.72 | PTGS1 (0.72) | CYP2C19ALDH1A1LMNAKDM4EGRM5 | |
| SCHEMBL28777566 | 0.71 | GRM1 (0.38) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL11813616 | 0.68 | TMEM97 (0.40) | CYP2C19ALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102447-A | Applying 1-(3-chlorophthalimido)cyclohexanecarboxamide to the roots, seeds, leaves or soil surrounding crops to prevent phytotoxic effects of terbufos | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | claimed |
| US-4933166-A | PHTHALIMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1990-06-12 | — | — | US | claimed |
| EP-0312762-A1 | Method of safening fungicidal compositions thereof | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0312763-A1 | Methods and compositions for protecting crop plants from undesirable effects of insecticidal compounds and herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | claimed |
| US-4933166-A | PHTHALIMIDE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0312763-A1 | Methods and compositions for protecting crop plants from undesirable effects of insecticidal compounds and herbicidal compounds | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |