Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680918 | 0.82 | CYP2C19 (0.74) | CYP2C19ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL10333162 | 0.81 | CYP2C19 (0.72) | CYP2C19ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL11729065 | 0.75 | CYP2C19 (0.71) | CYP2C19ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL11729073 | 0.71 | CYP2C19 (0.64) | CYP2C19ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL9770940 | 0.65 | ALDH1A1 (0.36) | CYP2C19ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL13642228 | 0.64 | HDAC1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL9770937 | 0.61 | PDE7A (0.31) | GAASMN1; SMN2 | |
| SCHEMBL406056 | 0.61 | CYP2C19 (0.47) | CYP2C19ALDH1A1LMNAHPGDGAA | |
| SCHEMBL18664787 | 0.59 | ALDH1A1 (0.60) | ALDH1A1LMNAHPGDGAAP2RX7 | |
| SCHEMBL24060059 | 0.59 | RAB9A (0.72) | ALDH1A1LMNAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427907-A2 | Substituted phthalimido cyclohexanecarboxamides and the use thereof for enhancing growth of hybrid tea rose plants | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |