SCHEMBL1172933

SCHEMBL1172933

N#CC(C#N)=C1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.46
ALDH1A1 P00352 5/20 0.46
GAA P10253 2/20 0.46
PKM P14618 2/20 0.46
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
POLB P06746 1/20 0.39
GPR35 Q9HC97 1/20 0.39
S100A4 P26447 1/20 0.38
TDP2 O95551 1/20 0.38
NSD2 O96028 1/20 0.38
PLA2G1B P04054 1/20 0.38
HSP90AA1 P07900 1/20 0.38
CCR6 P51684 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
KDM4E B2RXH2 1/20 0.36
EGFR P00533 2/20 0.35
HTT P42858 1/20 0.35
PIM1 P11309 1/20 0.34
USP8 P40818 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14873569 0.91 MAPT (0.49) MAPTALDH1A1GAAPKMMEN1
SCHEMBL10654735 0.86 MEN1 (0.52) MAPTALDH1A1GAAPKMMEN1
SCHEMBL16579336 0.85 MAPT (0.39) MAPTALDH1A1GAAPKMMEN1
SCHEMBL13302006 0.84 TDP2 (0.55) MAPTALDH1A1GAAPKMMEN1
SCHEMBL470752 0.83 MAPT (0.37) MAPTALDH1A1GAAPKMMEN1
SCHEMBL14570582 0.83 MAPT (0.37) MAPTALDH1A1GAAPKMMEN1
SCHEMBL30661156 0.83 MAPT (0.37) MAPTALDH1A1GAAPKMMEN1
SCHEMBL18725563 0.82 MAPT (0.46) MAPTALDH1A1GAAPKMMEN1
SCHEMBL27214112 0.82 PTPRC (0.47) MAPTALDH1A1GAAPKMMEN1
SCHEMBL27214106 0.82 PTPRC (0.47) MAPTALDH1A1GAAPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544453-B2 Photoreceptor with improved electron transport XEROX CORPORATION (US) 2009-06-09 US claimed
US-7294290-B2 Photochromic composition in a solid matrix NGX, INC. (US) 2007-11-13 US claimed
US-7235620-B2 Polyester having π-conjugated group in side chain and charge transporting material using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2007-06-26 US claimed
US-20070082283-A1 Photoreceptor with improved electron transport XEROX CORPORATION (US) 2007-04-12 US claimed
WO-2006009824-A2 PHOTOCHROMIC COMPOSITON IN A SOLID MATRIX NANOMAT, INC. (US) 2006-01-26 WO claimed
US-20050026072-A1 Photochromic composition in a solid matrix NGX, INC. 2005-02-03 US claimed
CN-1542556-A Organophotoreceptor with a charge transport material having two (9-fluorenylidene) malononitrile groups ���ǵ�����ʽ���� 2004-11-03 CN claimed
US-20040170909-A1 Organophotoreceptor with a charge transport material having two (9-fluorenylidene) malononitrile groups S-PRINTING SOLUTION CO., LTD. (KR) 2004-09-02 US claimed
EP-1452925-A1 Organophotoreceptor with a charge transport material having two (9-fluorenylidene) malononitrile groups Samsung Electronics Co., Ltd. (KR) 2004-09-01 EP claimed
US-RE29554-E Organic photoconductive members comprising dicyanomethylene substituted fluorene sensitizers ADDRESSOGRAPH-MULTIGRAPH CORPORATION (US) 1978-02-28 US claimed
US-4069046-A Polymerized vinyl carbazoles sensitized by nitro-substituted 9-dicyanomethylene fluorenes XEROX CORPORATION (US) 1978-01-17 US claimed
CN-110941154-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2025-05-16 CN disclosed
CN-110361942-B Electrophotographic photoreceptor, process cartridge, image forming apparatus, and imide compound 富士胶片商业创新有限公司 2024-04-05 CN disclosed
CN-108803266-B Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus 佳能株式会社 2022-03-15 CN disclosed
US-11222249-B2 Optically configurable charge-transfer materials and methods thereof NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2022-01-11 US disclosed
US-4069046-A Polymerized vinyl carbazoles sensitized by nitro-substituted 9-dicyanomethylene fluorenes XEROX CORPORATION (US) 1978-01-17 US disclosed
US-4069046-A Polymerized vinyl carbazoles sensitized by nitro-substituted 9-dicyanomethylene fluorenes XEROX CORPORATION (US) 1978-01-17 US disclosed
US-4046563-A PHOTOCONDUCTIVE COMPOSITION CONTAINING A TRICYANOPYRENE, ARTICLE AND PROCESS OF USE XEROX CORPORATION (US) 1977-09-06 US disclosed
US-4006017-A Photoconductive composition, article and process XEROX CORPORATION (US) 1977-02-01 US disclosed
US-3972717-A DYE, PHOTOCONDUCTOR HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040170909-A1 Organophotoreceptor with a charge transport material having two (9-fluorenylidene) malononitrile groups SLC39A14, SLC37A4, SLC39A7 MAPT 2355/4885ALDH1A1 1475/4885GAA 1156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.