SCHEMBL470752

SCHEMBL470752

N#CC(C#N)=C1c2ccccc2-c2c1c1c(c3c2C(=C(C#N)C#N)c2ccccc2-3)C(=C(C#N)C#N)c2ccccc2-1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.37
ALDH1A1 P00352 5/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
GPR35 Q9HC97 1/20 0.36
GAA P10253 2/20 0.35
PKM P14618 1/20 0.34
HPRT1 P00492 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HTT P42858 1/20 0.33
EGFR P00533 3/20 0.33
PDK2 Q15119 1/20 0.32
ESR2 Q92731 1/20 0.31
PIM1 P11309 1/20 0.31
S100A4 P26447 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30661156 1.00 MAPT (0.37) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL18904939 0.92 MAPT (0.34) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL1172933 0.83 MAPT (0.46) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL20015776 0.79 MAPT (0.34) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL470766 0.79 ALDH1A1 (0.38) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL16579336 0.79 MAPT (0.39) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL22109070 0.78 ALDH1A1 (0.31) MAPTALDH1A1GPR35
SCHEMBL14570582 0.77 MAPT (0.37) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL13064298 0.77 ALDH1A1 (0.40) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL20015768 0.77 MAPT (0.33) MAPTALDH1A1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4242216-A2 ELECTRONIC DEVICE AND COMPOUND Novaled GmbH (DE) 2023-09-13 EP disclosed
US-10941144-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-03-09 US disclosed
US-10840456-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-11-17 US disclosed
EP-3667752-A1 ELECTRONIC DEVICE AND COMPOUND Novaled GmbH (DE) 2020-06-17 EP disclosed
EP-2724388-B1 ELECTRONIC DEVICE NOVALED GMBH (DE) 2020-03-11 EP disclosed
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-09-24 US disclosed
US-10403824-B2 Electronic device and compound NOVALED GMBH (DE) 2019-09-03 US disclosed
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-03-21 US disclosed
US-20180179206-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD., (JP) 2018-06-28 US disclosed
US-20170155047-A1 Electronic Device and Compound NOVALED GMBH (DE) 2017-06-01 US disclosed
US-9502660-B2 Electronic device and compound NOVALED GMBH (DE) 2016-11-22 US disclosed
EP-2614047-B1 COMPOUNDS FOR ORGANIC PHOTOVOLTAIC DEVICES NOVALED AG (DE) 2016-10-26 EP disclosed
US-20140182681-A1 Electronic Device and Compound NOVALED GMBH (DE) 2014-07-03 US disclosed
US-20140144509-A1 Compounds for Organic Photovoltaic Devices NOVALED AG (DE) 2014-05-29 US disclosed
US-20140144509-A1 Compounds for Organic Photovoltaic Devices NOVALED AG (DE) 2014-05-29 US disclosed
WO-2012031735-A1 COMPOUNDS FOR ORGANIC PHOTOVOLTAIC DEVICES NOVALED AG (DE) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180179206-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE L1CAM, ESR1, CHRM1 MAPT 1871/4885ALDH1A1 83/4885KMT2A 1458/4885
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM MAPT 2451/4885ALDH1A1 404/4885KMT2A 1284/4885
US-10403824-B2 Electronic device and compound BRIX1, C9, C1S MAPT 4822/4885ALDH1A1 859/4885KMT2A 4323/4885
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device PIEZO1, LEF1, L1CAM MAPT 2451/4885ALDH1A1 404/4885KMT2A 1284/4885
US-20170155047-A1 Electronic Device and Compound BRIX1, C9, C1S MAPT 4822/4885ALDH1A1 859/4885KMT2A 4323/4885
US-10941144-B2 Organic electroluminescence device and electronic device L1CAM, ESR1, CHRM1 MAPT 1871/4885ALDH1A1 83/4885KMT2A 1458/4885
US-10840456-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device L1CAM, PIEZO1, LEF1 MAPT 932/4885ALDH1A1 21/4885KMT2A 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.