Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734695 | 0.98 | HRH3 (0.49) | TDP1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5023581 | 0.88 | TDP1 (0.63) | TDP1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14114079 | 0.86 | LMNA (0.54) | TDP1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL18239140 | 0.83 | TDP1 (0.50) | TDP1LMNASMN1; SMN2MAPK1RARB | |
| SCHEMBL17445912 | 0.82 | ALDH1A1 (0.66) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL11736287 | 0.81 | TDP1 (0.51) | TDP1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11737700 | 0.80 | SMN1; SMN2 (0.46) | TDP1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17445914 | 0.80 | HRH3 (0.64) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL11737519 | 0.80 | MAOA (0.44) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL16560386 | 0.79 | LMNA (0.59) | LMNASMN1; SMN2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025641-A | INSECTICIDES, ACARICIDES | SANDOZ LTD. (CH) | 1977-05-24 | — | — | US | disclosed |