Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031252 | 0.83 | LMNA (0.40) | CA9CA12CA1CA2LMNA | |
| SCHEMBL18372009 | 0.80 | GAA (0.36) | GAACHRNB2CHRNA4SMN1; SMN2KDM4E | |
| SCHEMBL27734916 | 0.76 | LMNA (0.35) | CA9CA12CA1CA2LMNA | |
| SCHEMBL5086903 | 0.74 | HTR2A (0.46) | NPC1RAB9ASMN1; SMN2RET | |
| SCHEMBL11262616 | 0.73 | CA12 (0.33) | CA9CA12CA1CA2LMNA | |
| SCHEMBL25959557 | 0.72 | CA12 (0.41) | CA9CA12CA1CA2LMNA | |
| SCHEMBL13731973 | 0.68 | LMNA (0.38) | CA9CA12CA1CA2LMNA | |
| SCHEMBL2038159 | 0.67 | ACHE (0.45) | DRD1 | |
| SCHEMBL30918006 | 0.67 | ACHE (0.45) | DRD1 | |
| SCHEMBL7871371 | 0.67 | ACHE (0.45) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414195-B | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL CO | 2014-11-12 | — | — | CN | disclosed |
| CN-102414195-A | Fused heterocyclic compound and use thereof | SUMITOMO CHEMICAL CO | 2012-04-11 | — | — | CN | disclosed |
| EP-2424856-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010125985-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-04 | — | — | WO | disclosed |