Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731552 | 0.89 | HPGD (0.45) | RAB9ATSHRHPGDNPC1SMN1; SMN2 | |
| SCHEMBL11733336 | 0.89 | CYP1A2 (0.48) | RAB9AHPGDSMN1; SMN2TDP1CYP1A2 | |
| SCHEMBL11730730 | 0.87 | HPGD (0.40) | RAB9ATSHRHPGDNPC1SMN1; SMN2 | |
| SCHEMBL11731518 | 0.87 | TSHR (0.40) | RAB9ATSHRHPGDNPC1SMN1; SMN2 | |
| SCHEMBL11730723 | 0.87 | HPGD (0.40) | RAB9ATSHRHPGDNPC1SMN1; SMN2 | |
| SCHEMBL5725376 | 0.85 | RAB9A (0.54) | RAB9ATSHRHPGDNPC1SMN1; SMN2 | |
| SCHEMBL11850231 | 0.85 | PTGFR (0.58) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11514551 | 0.84 | SLC2A1 (0.44) | RAB9ATSHRHPGDNPC1SMN1; SMN2 | |
| Water SCHEMBL11730258 | 0.84 | PTGFR (0.57) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11730106 | 0.81 | TBXA2R (0.53) | TBXA2RPTGER1PTGFRPTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |