Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729979 | 0.89 | RAB9A (0.44) | HPGDSMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL11726349 | 0.89 | TDP1 (0.43) | HPGDRAB9AALDH1A1MAPK1TDP1 | |
| SCHEMBL11730168 | 0.85 | TBXA2R (0.46) | ALDH1A1MAPK1TDP1KMT2A | |
| SCHEMBL11656073 | 0.82 | MAPT (0.45) | HPGDSMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL11728728 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPK1TDP1KMT2A | |
| SCHEMBL11848646 | 0.81 | MAPT (0.43) | HPGDSMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL11730758 | 0.81 | TDP1 (0.45) | ALDH1A1MAPK1MAPTTDP1KMT2A | |
| SCHEMBL11852601 | 0.80 | ALOX15 (0.40) | ALDH1A1 | |
| SCHEMBL11732380 | 0.80 | GRM2 (0.38) | ALDH1A1MAPK1TDP1KMT2A | |
| SCHEMBL11730979 | 0.79 | HPGD (0.44) | HPGDSMN1; SMN2ALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |