Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725302 | 0.90 | CYP1A2 (0.43) | HPGDRAB9ASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL11729979 | 0.87 | RAB9A (0.44) | TSHRHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11730723 | 0.82 | HPGD (0.40) | TSHRHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11730730 | 0.82 | HPGD (0.40) | TSHRHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11731509 | 0.81 | RAB9A (0.43) | TSHRHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11732616 | 0.81 | GRM2 (0.33) | — | |
| SCHEMBL11729149 | 0.81 | MAPT (0.46) | TSHRHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11727616 | 0.80 | LTA4H (0.39) | SMN1; SMN2KMT2A | |
| SCHEMBL11726216 | 0.80 | TSHR (0.42) | TSHRTDP1ALDH1A1MAPK1MAPT | |
| SCHEMBL11731325 | 0.80 | ADRB2 (0.40) | HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |