Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.50 |
| ▸ | MTOR | P42345 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11732890 | 0.85 | DRD2 (0.43) | PIK3CAMTORALDH1A1DRD2DRD3 | |
| SCHEMBL11733729 | 0.85 | KCNN4 (0.45) | PIK3CAMTORALDH1A1DRD2DRD3 | |
| SCHEMBL11730134 | 0.84 | ALDH1A1 (0.44) | PIK3CAMTORALDH1A1MEN1KMT2A | |
| SCHEMBL11730243 | 0.84 | DRD2 (0.44) | PIK3CAMTORALDH1A1DRD2DRD3 | |
| SCHEMBL11734384 | 0.83 | SMN1; SMN2 (0.54) | ALDH1A1DRD2DRD3KCNH2MEN1 | |
| SCHEMBL11735194 | 0.83 | DRD2 (0.41) | PIK3CAMTORALDH1A1DRD2DRD3 | |
| SCHEMBL11732830 | 0.81 | LMNA (0.44) | ALDH1A1EGFR | |
| SCHEMBL11729339 | 0.81 | ALDH1A1 (0.44) | ALDH1A1DRD2DRD3KCNH2MEN1 | |
| SCHEMBL11278353 | 0.80 | MEN1 (0.56) | PIK3CAMTORALDH1A1DRD2DRD3 | |
| SCHEMBL11733576 | 0.80 | MEN1 (0.48) | ALDH1A1ARMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009166-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, CNS DEPRESSANTS | HISAMITSU PHARMACEUTICAL CO., INC. (JA) | 1977-02-22 | — | — | US | claimed |
| US-4009166-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, CNS DEPRESSANTS | HISAMITSU PHARMACEUTICAL CO., INC. (JA) | 1977-02-22 | — | — | US | disclosed |