Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.41 |
| ▸ | HMGCR | P04035 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10917904 | 0.84 | CHRM1 (0.43) | CHRM1PTPN7HMGCRALDH1A1KDM4E | |
| SCHEMBL11733889 | 0.78 | PTPN7 (0.68) | CHRM1PTPN7HMGCRALDH1A1KDM4E | |
| SCHEMBL11408173 | 0.77 | CHRM1 (0.52) | CHRM1PTPN7HMGCRALDH1A1KDM4E | |
| SCHEMBL11408148 | 0.77 | PTPN7 (0.57) | CHRM1PTPN7HMGCRALDH1A1KDM4E | |
| SCHEMBL11287906 | 0.77 | PTPN7 (0.45) | CHRM1PTPN7HMGCRALDH1A1KDM4E | |
| SCHEMBL10945268 | 0.77 | ALDH1A1 (0.41) | PTPN7HMGCRALDH1A1KDM4ERECQL | |
| SCHEMBL11407276 | 0.76 | CHRM1 (0.50) | CHRM1PTPN7HMGCRALDH1A1KDM4E | |
| SCHEMBL11210943 | 0.76 | PTPN7 (0.48) | CHRM1PTPN7HMGCRALDH1A1KDM4E | |
| SCHEMBL96500 | 0.75 | — | — | |
| SCHEMBL9334669 | 0.74 | GPR84 (0.61) | PTPN7HMGCRALDH1A1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026911-A | CYANATION, HYDROLYSIS | MILES LABORATORIES, INC. (US) | 1977-05-31 | — | — | US | disclosed |