SCHEMBL1173304

SCHEMBL1173304

O=C(OC(=O)C(O)C(O)C(=O)O)c1cccnc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
KMT2A Q03164 5/20 0.52
LMNA P02545 4/20 0.52
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 2/20 0.51
APP P05067 1/20 0.50
GAA P10253 1/20 0.50
HCAR3 P49019 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ATM Q13315 1/20 0.46
MAPT P10636 2/20 0.45
F7 P08709 1/20 0.45
F3 P13726 1/20 0.45
SARM1 Q6SZW1 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.45
SIRT6 Q8N6T7 1/20 0.45
SIRT1 Q96EB6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25288322 0.94 ALDH1A1 (0.59) ALDH1A1KMT2ALMNATDP1KDM4E
SCHEMBL8838858 0.82 ALDH1A1 (0.52) ALDH1A1KMT2ALMNATDP1KDM4E
SCHEMBL436740 0.82 ALDH1A1 (0.52) ALDH1A1KMT2ALMNATDP1KDM4E
SCHEMBL811679 0.81 ALDH1A1 (0.60) ALDH1A1KMT2ALMNATDP1KDM4E
SCHEMBL810373 0.81 LMNA (0.55) ALDH1A1KMT2ALMNATDP1KDM4E
SCHEMBL6659868 0.80 ALDH1A1 (0.50) ALDH1A1KMT2ALMNATDP1KDM4E
SCHEMBL6658799 0.80 ALDH1A1 (0.50) ALDH1A1KMT2ALMNATDP1KDM4E
Cadaverine Tartrate SCHEMBL27880305 0.80 ALDH1A1 (0.60) ALDH1A1KMT2ALMNATDP1KDM4E
Water SCHEMBL27446035 0.80 ALDH1A1 (0.50) ALDH1A1KMT2ALMNATDP1KDM4E
Water SCHEMBL27446036 0.80 ALDH1A1 (0.50) ALDH1A1KMT2ALMNATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100029654-A1 CARDIOVASCULAR COMPOSITIONS AND USE OF THE SAME FOR THE TREATMENT OF ALZHEIMER'S DISEASE MOUNT SINAI SCHOOL OF MEDICINE 2010-02-04 US claimed
EP-2007385-A2 CARDIOVASCULAR COMPOSITION AND USE THE SAME FOR THE TREATMENT OF ALZHEIMERS DISEASE Mount Sinai School of Medicine (US) 2008-12-31 EP claimed
WO-2007112288-A2 CARDIOVASCULAR COMPOSITION AND USE THE SAME FOR THE TREATMENT OF ALZHEIMERS DISEASE MOUNT SINAI SCHOOL OF MEDICINE (US) 2007-10-04 WO claimed
EP-4464307-A1 COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME MPLUS COSMETICS S.R.L. (IT) 2024-11-20 EP disclosed
US-20240374498-A1 COSMETIC COMPOSITION AND METHODS OF MAKING THE SAME MPLUS COSMETICS S.R.L. (IT) 2024-11-14 US disclosed
CN-110637027-B Modified relaxin polypeptides comprising pharmacokinetic enhancers and uses thereof 百时美施贵宝公司 2024-08-30 CN disclosed
CN-116507315-A Silk-hyaluronic acid compositions for tissue filling, tissue spacing and tissue bulking 自然进化公司 2023-07-28 CN disclosed
CN-113403128-B High-molecular environment-friendly rolling liquid and preparation method and use method thereof 上海玺米惠新材料有限公司 2022-07-15 CN disclosed
CN-114068065-B Conductive material for temperature sensor and use thereof 杭州安誉科技有限公司 2022-07-08 CN disclosed
CN-114068065-A Conductive material for temperature sensor and use thereof 杭州安誉科技有限公司 2022-02-18 CN disclosed
CN-113403128-A High-molecular environment-friendly rolling liquid and preparation method and use method thereof 上海玺米惠新材料有限公司 2021-09-17 CN disclosed
WO-2003009819-A2 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS DOW CORNING CORPORATION (US) 2003-02-06 WO disclosed
US-6498197-B1 Temperature insensitive one-phase microemulsions DOW CORNING CORPORATION 2002-12-24 US disclosed
EP-1256336-A2 Two-phase gel composition Penreco (US) 2002-11-13 EP disclosed
US-20020055562-A1 Gel compositions WILMINGTON TRUST, NATIONAL ASSOCIATION 2002-05-09 US disclosed
EP-1141111-A1 GEL COMPOSITIONS Penreco (US) 2001-10-10 EP disclosed
WO-2000026285-A1 GEL COMPOSITIONS PENRECO (US) 2000-05-11 WO disclosed
US-5658576-A Method for combatting cellulitis or reducing localized fatty excesses L'OREAL (FR) 1997-08-19 US disclosed
US-5376374-A Cayenne pepper, calendula, echinacea, goldenseal, propolis, vinegar and water; alleviates gum disease ZELAYA LUZ M (US) 1994-12-27 US disclosed
US-4795638-A RUBEFACIENT, PLANT EXTRACT, POLYSILOXANE L'OREAL (FR) 1989-01-03 US disclosed