Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733249 | 1.00 | GRM2 (0.33) | GRM2TBXA2RCASRPTGER1PTGFR | |
| SCHEMBL11728906 | 0.87 | LTA4H (0.39) | TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11728916 | 0.87 | LTA4H (0.39) | TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11733734 | 0.87 | TBXA2R (0.38) | GRM2TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11729672 | 0.86 | PTGFR (0.38) | TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11729663 | 0.86 | PTGFR (0.38) | TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11732519 | 0.85 | CYP1A2 (0.43) | TBXA2R | |
| SCHEMBL11732510 | 0.85 | CYP1A2 (0.43) | TBXA2R | |
| SCHEMBL11734124 | 0.83 | TSHR (0.42) | TBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11736076 | 0.83 | ADRB2 (0.40) | TBXA2RPTGER1PTGFRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |