Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQLE | Q14534 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733389 | 1.00 | SQLE (0.47) | SQLEKMT2ALSSMAPTMEN1 | |
| SCHEMBL5656297 | 0.91 | — | — | |
| SCHEMBL5656303 | 0.91 | — | — | |
| SCHEMBL2456513 | 0.87 | KMT2A (0.50) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL2456517 | 0.87 | KMT2A (0.50) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL11866788 | 0.85 | CES2 (0.39) | SQLEKMT2ALSSMEN1ALOX15 | |
| SCHEMBL11866782 | 0.85 | CES2 (0.39) | SQLEKMT2ALSSMEN1ALOX15 | |
| SCHEMBL6708593 | 0.83 | FAAH (0.41) | KMT2ALSSMEN1ALOX15ALDH1A1 | |
| SCHEMBL6708601 | 0.83 | FAAH (0.41) | KMT2ALSSMEN1ALOX15ALDH1A1 | |
| SCHEMBL11549688 | 0.83 | KMT2A (0.50) | SQLEKMT2AMAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011335-A | INSECTICIDES, HORMONE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1977-03-08 | — | — | US | disclosed |