Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 13/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737998 | 0.90 | HPN (0.43) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11734771 | 0.82 | HPN (0.54) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11664373 | 0.76 | HDAC3 (0.33) | MAPTGAA | |
| SCHEMBL11661830 | 0.74 | CNR2 (0.35) | MAPTLMNA | |
| SCHEMBL11665590 | 0.74 | GABRA1 (0.34) | MAPTLMNA | |
| SCHEMBL647768 | 0.74 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL648287 | 0.74 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11736394 | 0.73 | HPN (0.54) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11742489 | 0.73 | HPN (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9328009 | 0.73 | HPN (0.58) | HPNMAPTALOX15SIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012523-A | Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-(thio or sulfonyl) alkanoic acids and derivatives | THE DOW CHEMICAL COMPANY (US) | 1977-03-15 | — | — | US | disclosed |