Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 12/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734636 | 0.90 | HPN (0.47) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11741056 | 0.84 | HPN (0.49) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11742489 | 0.82 | HPN (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11664373 | 0.80 | HDAC3 (0.33) | MAPTGAAXBP1ATMNPSR1 | |
| SCHEMBL11658758 | 0.77 | MAPT (0.41) | MAPTALOX15ATML3MBTL1 | |
| SCHEMBL8497146 | 0.76 | HPN (0.56) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL28406680 | 0.74 | ESR1 (0.44) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11740318 | 0.74 | VCAM1 (0.39) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11734771 | 0.72 | HPN (0.54) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL206201 | 0.72 | ESR1 (0.47) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012523-A | Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-(thio or sulfonyl) alkanoic acids and derivatives | THE DOW CHEMICAL COMPANY (US) | 1977-03-15 | — | — | US | disclosed |