Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805659 | 0.80 | DNM1 (0.48) | DNM1LPAR1LPAR3LPAR2THRB | |
| SCHEMBL155615 | 0.80 | DNM1 (0.48) | DNM1LPAR1LPAR3LPAR2THRB | |
| SCHEMBL28419293 | 0.80 | DNM1 (0.48) | DNM1LPAR1LPAR3LPAR2THRB | |
| SCHEMBL5596778 | 0.80 | DNM1 (0.48) | DNM1LPAR1LPAR3LPAR2THRB | |
| SCHEMBL31296257 | 0.80 | ADRB2 (0.38) | DNM1TSHR | |
| SCHEMBL1411254 | 0.78 | DNM1 (0.47) | DNM1LPAR1LPAR3LPAR2 | |
| SCHEMBL2330968 | 0.78 | DNM1 (0.47) | DNM1LPAR1LPAR3LPAR2 | |
| SCHEMBL25544295 | 0.78 | DNM1 (0.47) | DNM1LPAR1LPAR3LPAR2THRB | |
| SCHEMBL1411286 | 0.78 | DNM1 (0.47) | DNM1LPAR1LPAR3LPAR2 | |
| SCHEMBL497154 | 0.78 | DNM1 (0.42) | DNM1LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025641-A | INSECTICIDES, ACARICIDES | SANDOZ LTD. (CH) | 1977-05-24 | — | — | US | disclosed |