Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735893 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL11733170 | 0.89 | TP53 (0.37) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL11740117 | 0.88 | TP53 (0.39) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL11729010 | 0.88 | KDM4E (0.43) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL11736358 | 0.88 | KDM4E (0.41) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL11730627 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL11736073 | 0.87 | ALDH1A1 (0.38) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL10993418 | 0.86 | MAPT (0.41) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 | |
| SCHEMBL11735667 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2HSD17B10HPGDALDH1A1TP53 | |
| SCHEMBL11733914 | 0.86 | TP53 (0.49) | SMN1; SMN2LMNAHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041163-A | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents | PFIZER INC. (US) | 1977-08-09 | — | — | US | disclosed |