Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733455 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1GAAPKMTP53 | |
| SCHEMBL11738548 | 0.84 | TP53 (0.54) | KDM4EALDH1A1PARP10PARP15TNKS2 | |
| SCHEMBL11734087 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1TP53CHEK1LIMK1 | |
| SCHEMBL11729010 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1GAAPARP10TP53 | |
| SCHEMBL11471352 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1GAAPKMPARP10 | |
| SCHEMBL18747058 | 0.71 | PARP10 (0.51) | KDM4EALDH1A1PARP10PARP15TNKS2 | |
| SCHEMBL11359826 | 0.70 | PARP10 (0.47) | KDM4EALDH1A1GAAPKMPARP10 | |
| SCHEMBL11470557 | 0.69 | TP53 (0.37) | KDM4EALDH1A1GAAPKMTP53 | |
| SCHEMBL28427333 | 0.68 | IDO1 (0.62) | KDM4EALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL11471959 | 0.68 | KDM4E (0.60) | KDM4EALDH1A1GAAPKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041163-A | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents | PFIZER INC. (US) | 1977-08-09 | — | — | US | disclosed |