Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735261 | 0.84 | KDM4E (0.48) | TP53SMN1; SMN2MAPTPARP15PARP10 | |
| SCHEMBL11363546 | 0.82 | KDM4E (0.41) | TP53SMN1; SMN2MAPTPARP15PARP10 | |
| SCHEMBL11733455 | 0.81 | KDM4E (0.43) | TP53SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL11732938 | 0.79 | TP53 (0.51) | TP53SMN1; SMN2MAPTPARP15PARP10 | |
| SCHEMBL11734087 | 0.78 | KDM4E (0.54) | TP53SMN1; SMN2MAPTLMNAPDE3A | |
| SCHEMBL11486320 | 0.76 | TP53 (0.68) | TP53SMN1; SMN2MAPTPTPN11LMNA | |
| SCHEMBL10986041 | 0.74 | PARP15 (0.42) | TP53SMN1; SMN2MAPTPARP15PARP10 | |
| SCHEMBL20128396 | 0.73 | ALDH1A1 (0.58) | TP53SMN1; SMN2MAPTPARP15PARP10 | |
| SCHEMBL11351095 | 0.72 | TP53 (0.48) | TP53SMN1; SMN2MAPTPARP15PARP10 | |
| SCHEMBL11470557 | 0.71 | TP53 (0.37) | TP53SMN1; SMN2MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041163-A | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents | PFIZER INC. (US) | 1977-08-09 | — | — | US | disclosed |