Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352768 | 0.83 | GABRP (0.33) | KDM4EALDH1A1GAAPKMGABRP | |
| SCHEMBL11357161 | 0.81 | ALDH1A1 (0.32) | TP53KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11738548 | 0.71 | TP53 (0.54) | TP53KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11735261 | 0.69 | KDM4E (0.48) | TP53KDM4ESMN1; SMN2CHEK1LIMK1 | |
| SCHEMBL11734087 | 0.68 | KDM4E (0.54) | TP53KDM4ESMN1; SMN2CHEK1LIMK1 | |
| SCHEMBL11733455 | 0.64 | KDM4E (0.43) | TP53KDM4ESMN1; SMN2CHEK1LIMK1 | |
| SCHEMBL11471959 | 0.64 | KDM4E (0.60) | TP53KDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7089136 | 0.64 | HSD17B10 (0.46) | KDM4EALDH1A1GAAPKMMAPT | |
| SCHEMBL4303369 | 0.63 | HSD17B10 (0.44) | KDM4EALDH1A1GAAPKMMAPT | |
| SCHEMBL11389207 | 0.62 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232024-A | ANTIALLERGENS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-11-04 | — | — | US | disclosed |