Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584374 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL11734794 | 0.98 | ALDH1A1 (0.33) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL11732736 | 0.98 | ALDH1A1 (0.33) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL9323872 | 0.88 | LMNA (0.39) | MAPT | |
| SCHEMBL31086365 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL2525583 | 0.86 | LMNA (0.48) | — | |
| SCHEMBL31086378 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL9945701 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TDP1CA12CA1CA2 | |
| SCHEMBL25494759 | 0.82 | — | — | |
| SCHEMBL13684772 | 0.82 | LMNA (0.46) | ALDH1A1TDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025641-A | INSECTICIDES, ACARICIDES | SANDOZ LTD. (CH) | 1977-05-24 | — | — | US | disclosed |