Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734794 | 0.91 | ALDH1A1 (0.33) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11732736 | 0.91 | ALDH1A1 (0.33) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11736517 | 0.88 | ALDH1A1 (0.34) | MAPT | |
| SCHEMBL11584374 | 0.88 | ALDH1A1 (0.34) | MAPT | |
| SCHEMBL23666631 | 0.88 | LMNA (0.48) | LMNARARBMEN1THRBHTT | |
| SCHEMBL8011379 | 0.88 | LMNA (0.48) | LMNARARBMEN1THRBHTT | |
| SCHEMBL10498087 | 0.88 | LMNA (0.48) | LMNARARBMEN1THRBHTT | |
| SCHEMBL3715852 | 0.88 | LMNA (0.48) | LMNARARBMEN1THRBHTT | |
| SCHEMBL1925735 | 0.88 | LMNA (0.48) | LMNARARBMEN1THRBHTT | |
| SCHEMBL398667 | 0.88 | LMNA (0.48) | LMNARARBMEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401966-B1 | Phenethanolamine derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LTD (GB) | 1994-01-19 | — | — | EP | disclosed |
| US-5066678-A | PHENETHANDAMINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | GLAXO GROUP LIMITED (GB) | 1991-11-19 | — | — | US | disclosed |
| EP-0401966-A1 | Phenethanolamine derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1990-12-12 | — | — | EP | disclosed |