Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879291 | 0.75 | LMNA (0.39) | LMNA | |
| SCHEMBL26407307 | 0.73 | CA2 (0.34) | — | |
| SCHEMBL277921 | 0.72 | LMNA (0.45) | LMNA | |
| SCHEMBL9453456 | 0.72 | CASP2 (0.31) | LMNA | |
| SCHEMBL4669402 | 0.72 | LMNA (0.30) | LMNA | |
| SCHEMBL15902303 | 0.70 | LMNA (0.43) | LMNA | |
| SCHEMBL7795109 | 0.70 | LMNA (0.43) | LMNA | |
| SCHEMBL9768597 | 0.70 | CYP2C19 (0.45) | LMNA | |
| SCHEMBL25108744 | 0.70 | LMNA (0.35) | LMNA | |
| SCHEMBL21466313 | 0.70 | LMNA (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048312-A | 2,4-Diaminoquinazolines as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-3956495-A | 2,4-Diaminoquinazolines as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-05-11 | — | — | US | disclosed |