Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11736587 | 0.86 | AKR1C1 (0.58) | NPC1RAB9AFFAR1MAPTAKR1C1 | |
| SCHEMBL501923 | 0.83 | AKR1C1 (0.57) | AKR1C1OPRL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2722547 | 0.83 | AKR1C1 (0.57) | AKR1C1OPRL1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1804765 | 0.81 | AKR1C1 (0.55) | AKR1C1OPRL1MEN1KMT2AHSD11B1 | |
| SCHEMBL30662077 | 0.80 | AKR1C1 (0.46) | AKR1C1OPRL1LMNAHSD11B1 | |
| SCHEMBL28212693 | 0.76 | PARP10 (0.53) | FFAR1AKR1C1OPRL1LMNAKMT2A | |
| SCHEMBL4558687 | 0.76 | FFAR1 (0.47) | FFAR1AKR1C1OPRL1LMNA | |
| SCHEMBL2184245 | 0.76 | AKR1C1 (0.64) | AKR1C1OPRL1MEN1LMNAKMT2A | |
| SCHEMBL42114 | 0.76 | AKR1C1 (0.70) | AKR1C1OPRL1MEN1LMNAKMT2A | |
| SCHEMBL3816037 | 0.76 | FFAR1 (0.41) | NPC1RAB9AFFAR1MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042584-A | ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1977-08-16 | — | — | US | disclosed |