Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501923 | 1.00 | AKR1C1 (0.57) | AKR1C1HSD11B1OPRL1HDAC4MEN1 | |
| Hydrochloric Acid SCHEMBL1804765 | 0.98 | AKR1C1 (0.55) | AKR1C1HSD11B1OPRL1HDAC4MEN1 | |
| SCHEMBL42114 | 0.91 | AKR1C1 (0.70) | AKR1C1HSD11B1OPRL1HDAC4MEN1 | |
| SCHEMBL2184245 | 0.91 | AKR1C1 (0.64) | AKR1C1HSD11B1OPRL1HDAC4MEN1 | |
| SCHEMBL43810 | 0.90 | AKR1C1 (0.68) | AKR1C1HSD11B1OPRL1HDAC4MEN1 | |
| SCHEMBL30662077 | 0.88 | AKR1C1 (0.46) | AKR1C1HSD11B1OPRL1HDAC1 | |
| SCHEMBL2703559 | 0.86 | ALDH1A1 (0.58) | AKR1C1OPRL1HDAC1SMN1; SMN2CYP2C9 | |
| SCHEMBL8366154 | 0.86 | OPRL1 (0.56) | AKR1C1HSD11B1OPRL1HDAC4MEN1 | |
| SCHEMBL476403 | 0.86 | OPRM1 (0.58) | AKR1C1HSD11B1OPRL1HDAC4HDAC1 | |
| SCHEMBL7864618 | 0.86 | AKR1C1 (0.48) | AKR1C1HSD11B1OPRL1HDAC4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059933-A1 | A NEW PROCESS FOR PREPARING OPTICALLY PURE MILNACIPRAN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS. | ARCH PHARMALABS LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |