Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 9/20 | 0.52 |
| ▸ | BCHE | P06276 | 8/20 | 0.52 |
| ▸ | APP | P05067 | 8/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542576 | 0.81 | RAD52 (0.55) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL11734758 | 0.72 | CASP6 (0.62) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL16404352 | 0.70 | ACP1 (0.72) | ALDH1A1MAPTKMT2AACP1 | |
| SCHEMBL12175837 | 0.70 | RAD52 (1.00) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3542022 | 0.69 | MAPT (0.46) | ALDH1A1LMNAMAPT | |
| SCHEMBL11735120 | 0.69 | CASP6 (0.84) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9287754 | 0.68 | SUMO3 (0.72) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL4084505 | 0.68 | ACP1 (1.00) | LMNAMAPTKMT2AACP1TLR7 | |
| SCHEMBL1090319 | 0.68 | TLR9 (0.67) | RAD52KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL30456191 | 0.68 | APP (0.60) | KDM4EALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048312-A | 2,4-Diaminoquinazolines as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-3956495-A | 2,4-Diaminoquinazolines as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-05-11 | — | — | US | disclosed |