Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 8/20 | 0.53 |
| ▸ | ACHE | P22303 | 8/20 | 0.53 |
| ▸ | APP | P05067 | 7/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799832 | 0.84 | APP (0.58) | KMT2AMAPTBCHEACHEAPP | |
| SCHEMBL11737345 | 0.81 | RAD52 (0.54) | RAD52KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL17803701 | 0.79 | NR2F2 (0.62) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL2244134 | 0.75 | TAAR1 (0.49) | KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL2244129 | 0.75 | TAAR1 (0.49) | KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL30456191 | 0.74 | APP (0.60) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7498565 | 0.72 | TLR7 (0.51) | KMT2AKDM4EALDH1A1POLBTLR7 | |
| SCHEMBL12175837 | 0.71 | RAD52 (1.00) | RAD52KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL7501979 | 0.71 | HTR1A (0.59) | — | |
| SCHEMBL17800008 | 0.70 | SLC6A3 (0.62) | KMT2AMAPTBCHEACHEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0326329-A2 | Quinazoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |