Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.52 |
| ▸ | FOS | P01100 | 1/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16108766 | 0.84 | NR1H4 (0.60) | NR1H4KAT6AFOSJUNKMT2A | |
| SCHEMBL1436279 | 0.83 | NR1H4 (0.63) | NR1H4KAT6AFOSJUNKMT2A | |
| SCHEMBL931583 | 0.83 | NR1H4 (0.75) | NR1H4KAT6AFOSJUNKMT2A | |
| SCHEMBL920107 | 0.83 | HPGD (0.54) | NR1H4KAT6AGSK3BKMT2AALDH1A1 | |
| SCHEMBL637341 | 0.83 | KMT2A (0.54) | KAT6AGSK3BKMT2APTPN1ALDH1A1 | |
| SCHEMBL7260601 | 0.81 | PARP1 (0.60) | NR1H4KAT6AFOSJUNKMT2A | |
| SCHEMBL3248766 | 0.81 | NR1H4 (0.58) | NR1H4KAT6AFOSJUNKMT2A | |
| SCHEMBL6705940 | 0.81 | GSK3B (0.61) | NR1H4FOSJUNGSK3BUSP2 | |
| SCHEMBL31130233 | 0.80 | NR1H4 (0.54) | NR1H4KAT6AFOSJUNKMT2A | |
| SCHEMBL26049008 | 0.80 | NR1H4 (0.60) | NR1H4KAT6AFOSJUNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033978-A | Thiacycl[2.2.2]azine carboxylic acids | SYNTEX (U.S.A.) INC. (US) | 1977-07-05 | — | — | US | disclosed |