Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 9/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742144 | 0.86 | ALOX5 (0.44) | VCAM1GAAXBP1ATMNPSR1 | |
| SCHEMBL11657452 | 0.85 | PPARG (0.38) | PPARGALOX5PTGESPPARA | |
| SCHEMBL10883150 | 0.85 | VCAM1 (0.41) | VCAM1ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL11736305 | 0.84 | PPARG (0.46) | VCAM1PPARGALOX5PTGESPPARA | |
| SCHEMBL11742069 | 0.83 | PPARG (0.45) | VCAM1PPARGALOX5PTGESPPARA | |
| SCHEMBL10883443 | 0.82 | VCAM1 (0.42) | VCAM1GAAXBP1ATMNPSR1 | |
| SCHEMBL11742057 | 0.81 | HPN (0.40) | VCAM1GAAXBP1ATMNPSR1 | |
| SCHEMBL9326923 | 0.81 | VCAM1 (0.43) | VCAM1GAAALOX5HPNMAPT | |
| SCHEMBL11601063 | 0.80 | PPARG (0.49) | VCAM1PPARGALOX5PTGESPPARA | |
| SCHEMBL11599468 | 0.79 | HPN (0.41) | VCAM1GAAXBP1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012523-A | Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-(thio or sulfonyl) alkanoic acids and derivatives | THE DOW CHEMICAL COMPANY (US) | 1977-03-15 | — | — | US | disclosed |