Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 13/20 | 0.49 |
| ▸ | PTGES | O14684 | 10/20 | 0.49 |
| ▸ | PPARA | Q07869 | 12/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11599469 | 0.99 | PPARG (0.48) | PPARGALOX5PTGESPPARAHPN | |
| SCHEMBL11736305 | 0.96 | PPARG (0.46) | PPARGALOX5PTGESPPARAHPN | |
| SCHEMBL11742069 | 0.95 | PPARG (0.45) | PPARGALOX5PTGESPPARAHPN | |
| SCHEMBL7699000 | 0.92 | ALOX15 (0.45) | PPARGALOX5PTGESPPARAHPN | |
| SCHEMBL11599468 | 0.88 | HPN (0.41) | PPARGALOX5PTGESPPARAHPN | |
| SCHEMBL11739113 | 0.86 | HPN (0.41) | PPARGALOX5PTGESPPARAHPN | |
| SCHEMBL11736649 | 0.85 | HTT (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11598916 | 0.85 | MMP9 (0.44) | PPARGALOX5PTGESHPNMAPT | |
| SCHEMBL11649037 | 0.85 | LMNA (0.40) | PPARGALOX5PTGESPPARAHPN | |
| SCHEMBL11742144 | 0.85 | ALOX5 (0.44) | PPARGALOX5PTGESPPARAHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012523-A | Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-(thio or sulfonyl) alkanoic acids and derivatives | THE DOW CHEMICAL COMPANY (US) | 1977-03-15 | — | — | US | claimed |
| CN-110885488-B | Ultraviolet light irradiation low-smoke halogen-free cable material and preparation method thereof | 广东安拓普聚合物科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| US-4078084-A | Novel hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)thio carboxamides | THE DOW CHEMICAL COMPANY (US) | 1978-03-07 | — | — | US | disclosed |
| US-4076841-A | Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)thio carboxamides | THE DOW CHEMICAL COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4029812-A | Novel hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)thio carboxamides | THE DOW CHEMICAL COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4012523-A | Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-(thio or sulfonyl) alkanoic acids and derivatives | THE DOW CHEMICAL COMPANY (US) | 1977-03-15 | — | — | US | disclosed |