Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741256 | 0.87 | CASP3 (0.43) | NPC1RAB9AKMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11741645 | 0.82 | NPC1 (0.42) | NPC1RAB9AKMT2AKDM4ETDP1 | |
| SCHEMBL11743857 | 0.80 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4ETDP1 | |
| SCHEMBL11738748 | 0.80 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4ETDP1 | |
| SCHEMBL11743478 | 0.80 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4ETDP1 | |
| SCHEMBL11738260 | 0.79 | NPC1 (0.41) | NPC1RAB9AKMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11746962 | 0.79 | NPC1 (0.37) | NPC1RAB9AKMT2AKDM4ETDP1 | |
| SCHEMBL11736431 | 0.79 | NPC1 (0.37) | NPC1RAB9AKMT2AKDM4ETDP1 | |
| SCHEMBL11739663 | 0.79 | HRH3 (0.39) | NPC1RAB9AKMT2AKDM4ETDP1 | |
| SCHEMBL11737961 | 0.79 | NPC1 (0.37) | NPC1RAB9AKMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033977-A | ANTIINFLAMMATORY, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |