Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741172 | 0.87 | NPC1 (0.41) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11745607 | 0.84 | PKM (0.39) | CASP3SENP8SENP7SENP6PKM | |
| SCHEMBL11741941 | 0.81 | KDM4E (0.41) | CASP3SENP8SENP7SENP6PKM | |
| SCHEMBL11742742 | 0.76 | KDM4E (0.39) | CASP3SENP8SENP7SENP6KDM4E | |
| Hydrochloric Acid SCHEMBL11741645 | 0.70 | NPC1 (0.42) | KDM4ERAB9ANPC1MAPTKMT2A | |
| SCHEMBL943870 | 0.70 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL11738748 | 0.69 | NPC1 (0.38) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11743857 | 0.69 | NPC1 (0.38) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL2074075 | 0.69 | ALDH1A1 (0.42) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL11736431 | 0.67 | NPC1 (0.37) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033977-A | ANTIINFLAMMATORY, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |