Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11736261 | 0.85 | KDM4E (0.60) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL11736292 | 0.82 | KDM4E (0.51) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9700724 | 0.80 | KDM4E (0.66) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL7397061 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9525290 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9700710 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9526447 | 0.78 | GAA (1.00) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL11735164 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| SCHEMBL9701346 | 0.78 | KDM4E (0.64) | KDM4EGAAALDH1A1GLAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11731590 | 0.77 | CYBB (0.43) | KDM4EGAAALDH1A1GLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053470-A | BACTERICIDES, ANTIBIOTICS | PARKE, DAVIS & COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-3954734-A | PENICILLIN AND CEPHALOSPORIN TYPE | PARKE, DAVIS & COMPANY | 1976-05-04 | — | — | US | disclosed |
| US-3951982-A | Trialkylsilyl esters of 6(substituted amino)phenyl-1,-dihydro-2-oxonicotinic acid, methods for their production and conversion to the corresponding acid chlorides | PARKE, DAVIS & COMPANY | 1976-04-20 | — | — | US | disclosed |