Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128211 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KMT2AHTR2AGAAADRA2A | |
| SCHEMBL12247403 | 0.80 | SIGMAR1 (0.43) | ALDH1A1 | |
| SCHEMBL15848208 | 0.80 | CYP3A4 (0.35) | ALDH1A1KMT2AHTR2AGAA | |
| SCHEMBL779686 | 0.77 | KDM1A (0.51) | KMT2AHTR2A | |
| SCHEMBL22367769 | 0.75 | — | — | |
| SCHEMBL9413028 | 0.71 | ALDH1A1 (0.32) | ALDH1A1KMT2AHTR2AGAA | |
| SCHEMBL24146557 | 0.71 | KIF11 (0.33) | ALDH1A1KMT2AGAA | |
| SCHEMBL548107 | 0.71 | ALDH1A1 (0.33) | ALDH1A1KMT2AHTR2AGAA | |
| SCHEMBL29449822 | 0.70 | HTR2A (0.45) | ALDH1A1KMT2AHTR2AADRA2AADRA2B | |
| SCHEMBL10772805 | 0.69 | RARB (0.33) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013682-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1977-03-22 | — | — | US | disclosed |
| US-3978126-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1976-08-31 | — | — | US | disclosed |