Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | TP53 | P04637 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furazolidone SCHEMBL64996 | 1.00 | LMNA (1.00) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| Furazolidone SCHEMBL64995 | 1.00 | LMNA (1.00) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| Furazolidone SCHEMBL11235500 | 0.93 | LMNA (0.86) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL30514100 | 0.85 | LMNA (0.74) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| Nifuratel SCHEMBL28086242 | 0.84 | LMNA (0.70) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| Furazolidone SCHEMBL29754412 | 0.82 | LMNA (0.70) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| Nifuradene SCHEMBL151225 | 0.82 | LMNA (0.69) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| Nifuradene SCHEMBL151226 | 0.82 | LMNA (0.69) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| Furazolidone SCHEMBL28086650 | 0.80 | LMNA (0.64) | LMNAALDH1A1TP53SMN1; SMN2MAPT | |
| SCHEMBL14069664 | 0.78 | MAPT (0.64) | LMNAALDH1A1TP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012512-A | GROWTH-PROMOTING AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |