Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | TP53 | P04637 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 3/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nifuratel SCHEMBL16675657 | 0.93 | HIF1A (0.68) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Nifuratel SCHEMBL1649685 | 0.93 | HIF1A (0.68) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Nifuratel SCHEMBL365913 | 0.93 | HIF1A (0.68) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Nifuratel SCHEMBL153100 | 0.93 | HIF1A (0.68) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Nifuratel SCHEMBL15068213 | 0.93 | HIF1A (0.68) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Nifuratel SCHEMBL153098 | 0.93 | HIF1A (0.68) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Nifuratel SCHEMBL15375600 | 0.93 | HIF1A (0.68) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Nifuratel SCHEMBL28338979 | 0.92 | HIF1A (0.67) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Furazolidone SCHEMBL64995 | 0.84 | LMNA (1.00) | LMNAALDH1A1MAPTTP53SMN1; SMN2 | |
| Furazolidone SCHEMBL11742425 | 0.84 | LMNA (1.00) | LMNAALDH1A1MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |