Furazolidone

Furazolidone

SCHEMBL64995

O=C1OCCN1N=Cc1ccc([N+](=O)[O-])o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 1.00
ALDH1A1 P00352 7/20 1.00
TP53 P04637 6/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
MAPT P10636 4/20 1.00
CYP1A2 P05177 3/20 1.00
HIF1A Q16665 3/20 1.00
CYP2D6 P10635 2/20 1.00
ALOX15 P16050 1/20 1.00
ATM Q13315 1/20 1.00
MDM2 Q00987 4/20 0.62
TDP1 Q9NUW8 3/20 0.62
KDM4E B2RXH2 3/20 0.62
CYP3A4 P08684 3/20 0.62
ABCC4 O15439 1/20 0.62
TSHR P16473 1/20 0.62
MAOA P21397 1/20 0.62
CASP7 P55210 1/20 0.62
CISD1 Q9NZ45 1/20 0.62
HSD17B10 Q99714 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Furazolidone SCHEMBL64996 1.00 LMNA (1.00) LMNAALDH1A1TP53SMN1; SMN2MAPT
Furazolidone SCHEMBL11742425 1.00 LMNA (1.00) LMNAALDH1A1TP53SMN1; SMN2MAPT
Furazolidone SCHEMBL11235500 0.93 LMNA (0.86) LMNAALDH1A1TP53SMN1; SMN2MAPT
SCHEMBL30514100 0.85 LMNA (0.74) LMNAALDH1A1TP53SMN1; SMN2MAPT
Nifuratel SCHEMBL28086242 0.84 LMNA (0.70) LMNAALDH1A1TP53SMN1; SMN2MAPT
Furazolidone SCHEMBL29754412 0.82 LMNA (0.70) LMNAALDH1A1TP53SMN1; SMN2MAPT
Nifuradene SCHEMBL151225 0.82 LMNA (0.69) LMNAALDH1A1TP53SMN1; SMN2MAPT
Nifuradene SCHEMBL151226 0.82 LMNA (0.69) LMNAALDH1A1TP53SMN1; SMN2MAPT
Furazolidone SCHEMBL28086650 0.80 LMNA (0.64) LMNAALDH1A1TP53SMN1; SMN2MAPT
SCHEMBL14069664 0.78 MAPT (0.64) LMNAALDH1A1TP53SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15359 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
US-20260027140-A1 COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA ATOPIC MEDICAL INC (US) 2026-01-29 US claimed
US-12465623-B2 Use of parasites and extracellular vesicles obtained from parasites in cancer treatment YEDITEPE UNIVERSITESI (TR) 2025-11-11 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
US-4591545-A Photosensitive image-forming material having a layer of photosensitive polyester modified with chain extender DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-05-27 US claimed
EP-0146738-A2 Antimicrobial animal feed additive compositions AMERICAN CYANAMID COMPANY (US) 1985-07-03 EP claimed
US-4402965-A FURAZOLIDONE Simoons, John R. A. (US) 1983-09-06 US claimed
US-4235236-A Device for dispensing drug by combined diffusional and osmotic operations ALZA CORPORATION (US) 1980-11-25 US claimed
US-4112230-A Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-05 US claimed
US-4102998-A INTRAUTERINE DEVICE WHICH RELEASES MEDICATION GUTNICK MORTON 1978-07-25 US claimed
US-4053593-A PREVENTING AND CURING DISEASES IN FISH FRUMOFF LEW 1977-10-11 US claimed
US-4049817-A MICROBIOCIDE 6-CHLORO-BENZISOTHIAZOLINONE AND A 2-NITRO-FURYL OR 2-NITRO-THIENYL COMPOUND SANDOZ LTD. (CH) 1977-09-20 US claimed
US-4024327-A Baking finishes which do not pollute the environment BASF AKTIENGESELLSCHAFT (DT) 1977-05-17 US claimed
US-3980434-A THIN LAYER CHROMATOGRAPHY, FLUORESCENCE MORTON-NORWICH PRODUCTS, INC. (US) 1976-09-14 US claimed