Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 4/20 | 0.81 |
| ▸ | PGR | P06401 | 7/20 | 0.73 |
| ▸ | AR | P10275 | 5/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paramethasone Acetate SCHEMBL9270992 | 0.90 | ABCB11 (1.00) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone Acetate SCHEMBL13929947 | 0.90 | ABCB11 (1.00) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone Acetate SCHEMBL11443533 | 0.90 | ABCB11 (1.00) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone Acetate SCHEMBL11070642 | 0.90 | ABCB11 (1.00) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone Acetate SCHEMBL7126 | 0.90 | ABCB11 (1.00) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone Acetate SCHEMBL11279748 | 0.90 | ABCB11 (1.00) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone Acetate SCHEMBL13423597 | 0.90 | ABCB11 (1.00) | ABCB11PGRARADRA1AADORA3 | |
| SCHEMBL11742966 | 0.89 | ABCB11 (0.76) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone SCHEMBL5188901 | 0.85 | PGR (1.00) | ABCB11PGRARADRA1AADORA3 | |
| Paramethasone SCHEMBL11856144 | 0.85 | PGR (1.00) | ABCB11PGRARADRA1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017615-A | ESPECIALLY USEFUL FOR ANTIINFLAMMATORY TOPICAL CORTICOIDS | SYNTEX CORPORATION (PM) | 1977-04-12 | — | — | US | disclosed |