Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743373 | 0.84 | ALDH1A1 (0.47) | RORCALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11612271 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1CRHBPATM | |
| SCHEMBL11743333 | 0.79 | ALDH1A1 (0.49) | RORCALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL11613744 | 0.77 | NPC1 (0.50) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11612279 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL24393521 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1CRHBPATM | |
| SCHEMBL21247872 | 0.68 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1CRHBPATM | |
| SCHEMBL5107006 | 0.68 | RAB9A (0.53) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL17796945 | 0.68 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL17289272 | 0.68 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |