Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CRHBP | P24387 | 3/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612271 | 0.87 | ALDH1A1 (0.62) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL11613737 | 0.84 | NPSR1 (0.47) | ALDH1A1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL28425336 | 0.82 | NPC1 (0.45) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL24393521 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL11743378 | 0.79 | RORC (0.42) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL21247872 | 0.75 | ALDH1A1 (0.67) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL11291473 | 0.72 | ALDH1A1 (0.62) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL11844605 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL7339073 | 0.72 | ALDH1A1 (0.69) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL1118866 | 0.71 | TRPM8 (0.53) | ALDH1A1MEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061723-A | FROM HYDROGEN FLUORIDE AND A BORON-OXYGEN CONTAINING COMPOUND ION | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |