Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | FCER2 | P06734 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739271 | 0.94 | CYP1A2 (0.46) | CYP19A1CYP1A2CYP2A6DAOSLC6A2 | |
| SCHEMBL8246371 | 0.82 | XDH (0.46) | CYP19A1CYP1A2CYP2A6DAOSLC6A2 | |
| SCHEMBL8499487 | 0.79 | CYP1A2 (0.48) | CYP19A1CYP1A2CYP2A6DAOSLC6A2 | |
| SCHEMBL11737832 | 0.78 | CYP1A2 (0.57) | CYP1A2CYP2A6DAORAB9ABCHE | |
| SCHEMBL16595322 | 0.77 | SLC6A2 (0.46) | CYP19A1CYP1A2CYP2A6DAOSLC6A2 | |
| SCHEMBL1876507 | 0.77 | CYP19A1 (0.48) | CYP19A1 | |
| SCHEMBL720558 | 0.77 | CYP1A2 (0.56) | CYP1A2CYP2A6RAB9A | |
| SCHEMBL29955760 | 0.77 | CYP1A2 (0.56) | CYP1A2CYP2A6RAB9A | |
| SCHEMBL8499344 | 0.76 | SLC6A2 (0.45) | CYP19A1CYP1A2CYP2A6DAOSLC6A2 | |
| SCHEMBL11742739 | 0.76 | CYP2A6 (0.56) | CYP1A2CYP2A6BACE1HTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045485-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC AND ANTIPRURITIC ACTIVITY | SYNTEX CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3960936-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SKIN DISORDERS | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
| US-3947472-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-03-30 | — | — | US | disclosed |
| US-3935273-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |