Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27578379 | 0.95 | PIM1 (0.32) | PIM1 | |
| SCHEMBL27557994 | 0.87 | — | — | |
| SCHEMBL111815 | 0.82 | ALOX15 (0.41) | PIM1 | |
| SCHEMBL21989330 | 0.76 | PIM1 (0.32) | PIM1 | |
| SCHEMBL9059406 | 0.73 | ALDH1A1 (0.37) | PIM1 | |
| SCHEMBL11743783 | 0.71 | KMT2A (0.57) | PIM1 | |
| SCHEMBL466542 | 0.71 | — | — | |
| SCHEMBL10625594 | 0.71 | MAPT (0.57) | PIM1 | |
| SCHEMBL10692447 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL11681717 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353724-A | Method for polymerization of olefin | BASF AG (DE) | 2002-06-12 | — | — | CN | disclosed |