Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.30 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745254 | 0.82 | CYP17A1 (0.37) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL11745251 | 0.82 | CYP17A1 (0.37) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL11743388 | 0.82 | PGR (0.32) | PGRARNR3C2LMNANR1I2 | |
| SCHEMBL11747455 | 0.78 | CYP19A1 (0.31) | — | |
| SCHEMBL11747464 | 0.78 | CYP19A1 (0.31) | — | |
| SCHEMBL11516496 | 0.76 | LMNA (0.33) | PGRLMNANR1I2NR3C1 | |
| SCHEMBL11516494 | 0.76 | LMNA (0.33) | PGRLMNANR1I2NR3C1 | |
| SCHEMBL11747968 | 0.73 | LMNA (0.31) | PGRLMNANR1I2NR3C1 | |
| SCHEMBL11747974 | 0.73 | LMNA (0.31) | PGRLMNANR1I2NR3C1 | |
| SCHEMBL11744396 | 0.73 | CYP19A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058539-A | 4,6,8(14)-Triene steroids | STEELE CHEMICALS CO. LTD. (CA) | 1977-11-15 | — | — | US | disclosed |