Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384437 | 0.91 | LMNA (0.64) | HSD17B10POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL179087 | 0.88 | LMNA (0.60) | ALDH1A1LMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30544976 | 0.86 | ALDH1A1 (0.62) | ALDH1A1CYP3A4LMNASMN1; SMN2RAB9A | |
| SCHEMBL2730357 | 0.86 | ALDH1A1 (0.62) | ALDH1A1CYP3A4LMNASMN1; SMN2RAB9A | |
| SCHEMBL25987647 | 0.85 | SMN1; SMN2 (0.74) | HSD17B10POLBALDH1A1CYP3A4LMNA | |
| SCHEMBL13853584 | 0.85 | RAB9A (0.58) | HSD17B10POLBALDH1A1CYP3A4LMNA | |
| SCHEMBL179083 | 0.85 | LMNA (0.64) | POLBALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL4741336 | 0.85 | LMNA (0.57) | ALDH1A1LMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4991673 | 0.84 | SMN1; SMN2 (0.73) | HSD17B10ALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL5540748 | 0.84 | POLB (0.56) | HSD17B10POLBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| US-4065473-A | Intermediates in the preparation of 2,3,4,5-tetrahydro-1H-3-benzazepines | HOFFMANN-LA ROCHE INC. (US) | 1977-12-27 | — | — | US | disclosed |